This study shows how historic redlining practices and racial and socioeconomic composition affect present-day life expectancy. Using United States Census tracts as a proxy for neighborhoods, this study also controls for the impact of present-day demographics on the relationship between redlining and life expectancy. Data used were obtained from Diversity Data Kids and The Centers for Disease Prevention and Control. My sample comprises five cities (one from each region) and 3,160 census tracts. The regression results show that historic HOLC neighborhood grades are associated with present-day disparities in life expectancy, with racial and class composition serving as primary mechanisms by which that relationship rests. Findings also suggest regional differences in the extent of redlining's effect on life expectancy.