This study addresses the structural and organizational factors that are associated with varying levels of patient safety in hospitals across the U.S. With a sample of 1,171 nurses across 27 hospitals, I use t-tests and logistic regression analysis to examine the factors that have an association with nurse perceptions of patient safety. The subjective nature of this study focuses on nurse perceptions of quality care. Frequent pressure, dysfunction, and a lack of collaboration between nurses and physicians as felt by nurses prove to be associated with poor patient safety in hospitals. The aim of this study is twofold: 1) to bring attention to the prevalence of medical errors due to a lack of patient safety in our hospitals; and 2) to highlight the factors that are creating unsafe environments for patients in hopes of guiding future policymakers, labor-rights activists, and healthcare organizations to put patients first.